Abstract Background USP54, a ubiquitin-specific protease in the deubiquitinase (DUB) family, facilitates the malignant progression of several types of cancer.However, the role of USP54 in prostate cancer (PCa), especially castration-resistant prostate cancer (CRPC), remains unknown.Methods We established the CRPC LNCaP-AI cell line from the hormone
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Relationships linking travel speeds with the risk of casualty crashes have been combined with on-road speed surveys to estimate the proportion of crashes associated with each speed range and potentially attributable to speeding at different levels.This paper used speeds recorded by mobile speed cameras operated covertly in Melbourne 60 km/h speed l
Pressure is increasing on not-for-profit hospitals to demonstrate that they provide sufficient benefit to the community to justify their tax-exempt status.Many industry observers have suggested that this community benefit should address unmet footjoy weste herren medical needs within the community, deficits in the social determinants of health, or
Hepatitis C virus (HCV) is a major human pathogen that requires a better understanding of its interaction with host cells.There is a close association of HCV life cycle with host lipid metabolism.Lipid droplets (LDs) have been found to be crucial organelles that support HCV replication and virion assembly.In addition to their role in replication, L